pentobarbital will decrease the extent or result of buprenorphine buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or result of alosetron by influencing hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Not known.
Minor (one)pentobarbital will decrease the level or effect of paclitaxel protein certain by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will minimize the level or impact of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Powerful CYP3A4 inducers may perhaps minimize suvorexant efficacy; if enhanced suvorexant dose expected, never exceed 20 mg/day
pentobarbital will reduce the level or effect of abiraterone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Observe Intently (2)pentobarbital will reduce the level or influence of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. If coadministration that has a CYP3A4 inducer is essential, think about increasing oliceridine dose until finally steady drug effects are reached; observe for indications of click here opioid withdrawal.
pentobarbital will reduce the level or outcome of acalabrutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Contraindicated (1)pentobarbital will reduce the extent or result of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the level or impact of etravirine by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or outcome of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or influence of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is usually a sensitive CYP3A4 substrate. Coadministration with potent or reasonable CYP3A4 inducers is contraindicated.
pentobarbital will decrease the extent or outcome of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Reasonable CYP3A4 inducers may well decrease progestin concentration; take into account use of added barrier approaches
pentobarbital will lower the level or outcome of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Powerful CYP3A4 inducers may lessen midostaurin concentrations leading to decreased efficacy.
pentobarbital will decrease the extent or result of nicardipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.